Prof. Chris Seebregts has a background in biomedical research, computer science and information systems as well as more than twenty years experience in the research and development of digital health solutions in the public, private and academic sectors. He is the founder and Chief Executive Officer of Jembi Health Systems NPC, a South African non-profit company with an accomplished track record in developing and implementing innovative digital health information systems in low resource settings, particularly in Africa. He has participated in establishing health informatics academic and training programmes at two universities in South Africa and has honorary academic appointments in computer science and health at the universities of KwaZulu-Natal and Cape Town in South Africa. He is part of the leadership of several international open source health informatics communities, including the Open Medical Record System (www.openmrs.org) and the Open Health Information Exchange (www.ohie.org) communities. His research interests include biomedical and health informatics especially the development of health information systems supporting public health systems in Africa and the underlying burden of disease. He has a particular interest in the development of systems with a reusable architecture. As principle or co-Investigator on projects funded by international donors and funders, he has laid the groundwork for the development of advanced information systems supporting HIV/AIDS, TB, maternal and newborn health. More recently, he has been involved in the development of national digital health systems, at scale, and chronic disease management programmes.